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Cristina Borradori Tolsa, Slava Zimine, Simon K Warfield, Monica Freschi, Ana Sancho Rossignol, François Lazeyras, Sylviane Hanquinet, Mirjam Pfizenmaier, and Petra S Hüppi. 2004. “Early alteration of structural and functional brain development in premature infants born with intrauterine growth restriction”. Pediatr Res, 56, 1, Pp. 132-8.
Placental insufficiency with fetal intrauterine growth restriction (IUGR) is an important cause of perinatal mortality and morbidity and is subsequently associated with significant neurodevelopmental impairment in cognitive function, attention capacity, and school performance. The underlying biologic cause for this association is unclear. Twenty-eight preterm infants (gestational age 32.5 +/- 1.9 wk) were studied by early and term magnetic resonance imaging (MRI). An advanced quantitative volumetric three-dimensional MRI technique was used to measure brain tissue volumes in 14 premature infants with placental insufficiency, defined by abnormal antenatal Doppler measurements and mean birth weightsLast updated on 02/24/2023