Neuroimage Analysis Center
"understanding the human brain through imaging"


A Feature-based Developmental Model of the Infant Brain in Structural MRI

Top: distribution p(fi , A) for the 20 most significant age-related features over 10 age categories. Below: visual examples of features (white circles) in subject image slices over age. Pairs (4, 8) and (1,19) represent symmetric white matter patterns appearing at slightly different onsets. (7) and (9) represent distinct modes cerebellar anatomy linked with vermian development and occurring exclusively in early life. (13) occurs in the brain stem across the age range, more frequently in early life. Note the lack of visible white matter under 100 days, e.g. corpus callosum.


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The Neuroimage Analysis Center (NAC) develops image processing and analysis techniques for basic and clinical neurosciences. The NAC research approach emphasizes both specific core technologies and collaborative application projects. The activities of the NAC are centered at the Harvard Medical School and the Surgical Planning Laboratory at the Brigham and Women's Hospital in Boston, with collaborators throughout the United States and the rest of the world.

The NAC is a Biomedical Technology Resource Center supported by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) (P41 EB015902). It was supported by the National Center for Research Resources (NCRR) (P41 RR13218) through December 2011.

Surgical Planning LaboratoryBrigham and Women's HospitalHarvard Medical SchoolNational Center for Research Resources (NCRR)National Institute of Biomedical Imaging and Bioengineering (NIBIB)National Institute of Health (NIH)