Neuroimage Analysis Center
"understanding the human brain through imaging"


NMR diffusion-encoding with axial symmetry and variable anisotropy: Distinguishing between prolate and oblate microscopic diffusion tensors with unknown orientation distribution.

Axially symmetric diffusion-encoding with variable anisotropy b. (Top) Gradient unit vectors n11 (red), n2 (green), and n3 (blue) corresponding to the colors and numbered braces of the pulse sequence. The vectors are located with three-fold symmetry about the z-axis according to Eqs. (20) and (21). The inclination ζ gives the value of b through Eq. (24). (Middle) checkerboard plot of the b-tensor elements calculated with Eq. (22). The gray scale of element i j is given by bi j/b. (Bottom) visualization of the b-tensors as superquadrics.


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The Neuroimage Analysis Center (NAC) develops image processing and analysis techniques for basic and clinical neurosciences. The NAC research approach emphasizes both specific core technologies and collaborative application projects. The activities of the NAC are centered at the Harvard Medical School and the Surgical Planning Laboratory at the Brigham and Women's Hospital in Boston, with collaborators throughout the United States and the rest of the world.

The NAC is a Biomedical Technology Resource Center supported by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) (P41 EB015902). It was supported by the National Center for Research Resources (NCRR) (P41 RR13218) through December 2011.

Surgical Planning LaboratoryBrigham and Women's HospitalHarvard Medical SchoolNational Center for Research Resources (NCRR)National Institute of Biomedical Imaging and Bioengineering (NIBIB)National Institute of Health (NIH)