Neuroimage Analysis Center
"understanding the human brain through imaging"

O'Donnell-Neuroimage2012

fMRI-DTI Modeling via Landmark Distance Atlases for Prediction and Detection of Fiber Tracts

Leave-one-out prediction of tract location according to the landmark distance atlas (LDA). Each subject's fMRI activation peaks and anatomic landmarks, plus the leave-one-out LDA from the other subjects, were used to predict the location of the AF, left CST, and right CST. The true structures for each subject are shown in dark blue, and the 68% confidence interval for the predicted trajectory is shown in transparent cyan. These results provide an alternative visualization of the data in the learned landmark distance model and they demonstrate reasonable model generalization to novel subjects.

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The Neuroimage Analysis Center (NAC) develops image processing and analysis techniques for basic and clinical neurosciences. The NAC research approach emphasizes both specific core technologies and collaborative application projects. The activities of the NAC are centered at the Harvard Medical School and the Surgical Planning Laboratory at the Brigham and Women's Hospital in Boston, with collaborators throughout the United States and the rest of the world.

The NAC is a major research center supported by the National Center for Research Resources (through December 2011) and the Institute of Biomedical Imaging and Bioengineering (NIBIB), components of the National Institutes of Health.

Surgical Planning LaboratoryBrigham and Women's HospitalHarvard Medical SchoolNational Center for Research Resources (NCRR)National Institute of Biomedical Imaging and Bioengineering (NIBIB)National Institute of Health (NIH)