Trajectory control of PbSe-gamma-Fe2O3 nanoplatforms under viscous flow and an external magnetic field

Citation:

Etgar L, Nakhmani A, Tannenbaum A, Lifshitz E, Tannenbaum R. Trajectory control of PbSe-gamma-Fe2O3 nanoplatforms under viscous flow and an external magnetic field. Nanotechnology. 2010;21 (17) :175702.

Date Published:

2010 Apr 30

Abstract:

The flow behavior of nanostructure clusters, consisting of chemically bonded PbSe quantum dots and magnetic gamma-Fe(2)O(3) nanoparticles, has been investigated. The clusters are regarded as model nanoplatforms with multiple functionalities, where the gamma-Fe(2)O(3) magnets serve as transport vehicles, manipulated by an external magnetic field gradient, and the quantum dots act as fluorescence tags within an optical window in the near-infrared regime. The clusters' flow was characterized by visualizing their trajectories within a viscous fluid (mimicking a blood stream), using an optical imaging method, while the trajectory pictures were analyzed by a specially developed processing package. The trajectories were examined under various flow rates, viscosities and applied magnetic field strengths. The results revealed a control of the trajectories even at low magnetic fields (<1 T), validating the use of similar nanoplatforms as active targeting constituents in personalized medicine.
Last updated on 01/24/2017