A Dynamic Regression Approach for Frequency-Domain Partial Coherence and Causality Analysis of Functional Brain Networks

Date Published:

2018 Sep


Coherence and causality measures are often used to analyze the influence of one region on another during analysis of functional brain networks. The analysis methods usually involve a regression problem, where the signal of interest is decomposed into a mixture of regressor and a residual signal. In this paper, we revisit this basic problem and present solutions that provide the minimal-entropy residuals for different types of regression filters, such as causal, instantaneously causal, and noncausal filters. Using optimal prediction theory, we derive several novel frequency-domain expressions for partial coherence, causality, and conditional causality analysis. In particular, our solution provides a more accurate estimation of the frequency-domain causality compared with the classical Geweke causality measure. Using synthetic examples and in vivo resting-state functional magnetic resonance imaging data from the human connectome project, we show that the proposed solution is more accurate at revealing frequency-domain linear dependence among high-dimensional signals.

Last updated on 12/03/2018